- Baltimore Orioles release RP Brad Bergesen, OF Trent Mummey, RP Andrew Brackman, 3B Jason Espisito, 2B Ryan Adams, RP Robert Bundy and RP Dan Klein
- Boston Red Sox release SP Erik Bedard
- Philadelphia Phillies release OF Tyson Gillies
- Arizona Diamondbacks release RP Barry Enright, 1B Brandon Allen and 1B Juan Miranda
- Minnesota Twins release 3B Brent Morel
- Miami Marlins release RP Guillermo Mota
- Baltimore Orioles release SP Javier Vazquez, SP Chien-Ming Wang and RP Parker Bridewell
- Los Angeles Dodgers release 1B Matt LaPorta
- Philadelphia Phillies release C Josh Thole
- San Francisco Giants release 3B Conor Gillespie, RP Steve Edlefsen, SP Eric Surkamp and 1B Brett Pill
- Baltimore Orioles release RP Jason Isringhausen, SP Jonathan Sanchez and 3B Jason Esposito
- Toronto Blue Jays release RP Brian Fuentes and RP Josh Lueke
- New York Mets release 1B Zach Lutz
- St Louis Cardinals release Zack Cox and Yuniesky Betancourt
- Pittsburgh Pirates release RP Christopher Leroux
- Arizona Diamondbacks release OF Cole Gillespie and C Konrad Schmidt
- Houston Astros release SP Jon Garland
- Toronto Blue Jays release SS Mike McCoy and 1B Kyle Blanks
- Atlanta Braves release RP Josh Spence and SP Brad Penny
- Los Angeles Dodgers release SP Nick Blackburn
- Cleveland Indians release RP Blake Hawksworth and 1B Juan Miranda
- Cincinnati Reds release SS Kris Negron
- New York Yankees release INF Luke Hughes
- Los Angeles Angels release OF Jeremy Moore and C Brett Hayes
- Miami Marlins release RP Chad Qualls
- Oakland Athletics release SP Scott Baker
- Houston Astros release SS Angel Sanchez
- Kansas City Royals release RP Virgil Vasquez and RP Justin De Fratus
- Philadelphia Phillies release SP Tim Stauffer
- Miami Marlins release 1B Luis Durango
- Atlanta Braves release SP Guillermo Moscoso
- Arizona Diamondbacks release IF Ramon Santiago
- Oakland A's release OF Trayvon Robinson and SP Andrew Werner
- Oakland A's release OF Nyjer Morgan
- Arizona Diamondbacks release 3B Greg Dobbs and RP Esmerling Vasquez
- Oakland A's release RP Jeremy Jeffress
- Toronto Blue Jays release 1B David Cooper
